The subject of the study is the state of the global economy, determined by a set of negative trends caused by the coronavirus pandemic; the conduct of a special military operation in Ukraine and the related energy crisis; the military conflict in the Middle East in the Gaza Strip; rising inflation; an increase in the debt burden; the effects of climate change. The purpose of the work is to determine the possibilities of Russia to adapt to the new conditions of global development of the world economy. It is shown that the coming decade will be unique in terms of uncertainty and turbulence, or a “decade of polycrisis” due to the simultaneous intersection of different risk categories. It is proved that the stability of the Russian economy should be ensured by regionalization and reorientation to other world markets in spite of sanctions pressure; Russia’s participation in the formation of a broad Eurasian partnership based on the principles of equal and mutually beneficial cooperation; the development of the Northern Sea Route, which will make it possible to ensure communication with logistics hubs in the south of Eurasia. The global risks of the world economy on the horizon of two and ten years have been identified according to their degree of importance. The food price index compiled by the Food and Agriculture Organization of the United Nationsis considered. The method of reducing the investment imbalance in Russia through the wider application of the stabilization clause is substantiated. Conclusions are drawn about the need to build Russia’s state policy in the field of international cooperation without value political pressure on partner countries.